Buy Topamax (Topiramate) 25 mg Online
Buy Topamax Online
Drug family: Antiepileptic
01/11/2019: this drug is discontinued. It is no longer available in pharmacies or will no longer be available soon.
If you need to take this medication, talk to your doctor or pharmacist who will be able to advise you on an alternative treatment.
The document below represents the latest information published by Vidal concerning this drug and does not prejudge any changes that may have occurred since this publication.
This medication is a generic of EPITOMAX
WHEN IS TOPIRAMATE ARROW PRESCRIBED?
This medicine is an anti-epileptic. It has various properties that may explain its preventive effect on epileptic seizures: reduction in the excitability of neurons subjected to intensive stimulation; increase in the activity of a substance present in the brain: gamma-aminobutyric acid (GABA); reduction in the excitatory activity of glutamate on brain receptors. In migraine sufferers, it also has the property of spacing migraine attacks, although the mechanism of action is not clearly established.
It is used in the treatment of certain forms of epilepsy, alone or in combination with other antiepileptics.
It is also used in the background treatment of migraine in adults.
CONTRAINDICATIONS OF THE DRUG TOPIRAMATE ARROW
This drug should not be used in the background treatment of migraine in the following cases
women of childbearing age without effective contraception
pregnancy.
CAUTION
Studies have shown that the use of antiepileptic drugs may increase the risk of mood disorders, depression and, more rarely, suicidal behavior. If you experience a change in mood or morbid thoughts during treatment, tell your doctor immediately. The vigilance of the entourage is necessary.
This medication may cause an excess of acid in the blood; blood tests are usually prescribed before and during treatment to ensure that there are no abnormalities.
Precautions are necessary in cases of hepatic insufficiency, renal insufficiency and in persons prone to kidney stones.
The occurrence of a sudden drop in vision and/or severe eye pain requires urgent ophthalmological advice. This may be glaucoma.
Never change or stop your anti-epileptic treatment without your doctor's agreement: risk of recurrence of convulsions, even if no seizure has occurred for a long time.
Regular weight loss during treatment should be reported to your doctor.
Caution: driverDriving a car and using dangerous machines are contraindicated in epileptics when seizures persist despite preventive treatment. In addition, this drug may cause drowsiness or decreased alertness.
INTERACTIONS OF TOPIRAMATE ARROW WITH OTHER SUBSTANCES
This drug should not be used in combination with herbal products containing St. John's wort: risk of decreased antiepileptic effect.
It may decrease the effectiveness of oral contraceptives; an alternative method of contraception is recommended.
The use of drugs that increase the risk of kidney stones (mainly those containing methenamine) is not recommended.
Other antiepileptic drugs, such as carbamazepine or phenytoin, may interact with this drug: the physician should take this into account when prescribing.
FERTILITY, PREGNANCY AND LACTATION
PREGNANCY:
In the basic treatment of migraine, this drug is contraindicated during pregnancy and in women of childbearing age without an effective contraceptive method.
In epilepsy, women of childbearing age must use effective contraception during treatment. A desire to become pregnant requires medical advice and, when possible, the replacement of this medication with another antiepileptic drug. If pregnancy occurs while taking this medication, consult your physician promptly. Abruptly stopping an anti-epileptic drug treatment may lead to the recurrence of seizures that could be harmful to the mother and the unborn child. Your doctor will assess the possible risk of using this medication in your case. Special monitoring of pregnancy should be performed.
BREASTFEEDING:
Available data do not allow to know if this drug passes into breast milk; a choice is therefore necessary between breastfeeding and taking the drug. This decision should be made in consultation with your physician.
DIRECTIONS FOR USE AND DOSAGE OF TOPIRAMATE ARROW
This medication can be taken with or without meals.
The tablets are not suitable for children under 6 years of age. Indeed, they may obstruct the airways if the child swallows badly and the tablet passes into the trachea (false route).
USUAL DOSAGE :
In the treatment of epilepsy:
Adult: treatment is usually started at a dose of 25 mg per day. The dose is then gradually increased to 100 to 200 mg per day when used alone (not to exceed 500 mg per day) and 200 to 400 mg per day when combined with other antiepileptic drugs.
Children over 2 years of age: the dose depends on the child's weight and whether he or she is taking other antiepileptics. It is reached gradually, in steps of 1 or 2 weeks. Topiramate can be used alone in children aged 6 years and older. In children aged 2 to 6 years, it must be combined with other antiepileptic drugs.
In the background treatment of migraine:
Adult: 50 mg, twice daily. It is reached gradually.
ADVICE
Remember to drink enough, especially before and during physical effort or during hot weather. Dehydration favors certain undesirable effects (excess acid in the blood, urinary tract stones).
A decrease in perspiration and an increase in body temperature are possible under treatment. Make sure you cool down regularly (shower, wet towel...) in hot weather.
It is important to follow your anti-epileptic treatment rigorously: in order to avoid forgetting, it is preferable to take this medication at a fixed time; when you travel, carry a supply and a valid prescription.
POSSIBLE SIDE EFFECTS OF TOPIRAMATE ARROW
Very common: nausea, diarrhea, weight loss, cold, depression, tingling of the extremities, drowsiness, dizziness.
Common: vomiting, constipation, abdominal pain, anemia, loss of appetite, insomnia, difficulty finding words, anxiety, confusion or slowed thinking, disorientation, aggression, agitation, mood or behavioral problems, tremors, coordination problems, loss or decrease in taste, blurred or double vision, ringing in the ears
Uncommon: suicidal ideation, hallucinations, sleep disturbances, difficulty falling asleep, decreased libido, erectile dysfunction, difficulty concentrating and remembering things, dry eyes, light intolerance, palpitations, slow heartbeat, low blood pressure, flushing, shortness of breath, rash, itching, joint or muscle pain, abnormal blood counts, acidosis (excess acid in the blood), urinary tract stones
In children, learning difficulties have also been reported.
Rare: hepatitis, glaucoma (see Warning), allergic reaction.
At the beginning of treatment: paradoxical increase in the frequency of epileptic seizures or modification of their characteristics.
